Immaculate Conception School was established in 1924.  The first religious order to operate the school was the Sisters of the Blessed Sacrament.  Next, from 1939 to 1979, Immaculate Conception School was under the guidance of the School Sisters of Notre Dame.  Since 1979, the Salesian Sisters of St. John Bosco have directed Immaculate Conception School.  From its establishment, Immaculate Conception School has strived to provide an effective Catholic educational foundation for the children of  Marrero and the surrounding areas.